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1

Glucocorticoid insensitivity as a source of drug targets for respiratory disease

Ammit, Alaina J

Journal:

Current Opinion in Pharmacology

Year:

2013

Language:

english

File:

PDF, 268 KB

english, 2013

2

Repurposing of statins via inhalation to treat lung inflammatory conditions

Bradbury, Peta, Traini, Daniela, Ammit, Alaina J., Young, Paul M., Ong, Hui Xin

Journal:

Advanced Drug Delivery Reviews

Year:

2018

Language:

english

File:

PDF, 4.56 MB

english, 2018

3

New therapeutic targets for the prevention of infectious acute exacerbations of COPD: role of epithelial adhesion molecules and inflammatory pathways

Atto, Brianna, Eapen, Mathew Suji, Sharma, Pawan, Frey, Urs, Ammit, Alaina J., Markos, James, Chia, Collin, Larby, Josie, Haug, Greg, Weber, Heinrich C., Mabeza, George, Tristram, Stephen, Myers, Step

Journal:

Clinical Science

Year:

2019

Language:

english

File:

PDF, 1.71 MB

english, 2019

4

Regulation of ATP binding cassette transporter A1 (ABCA1) expression: cholesterol-dependent and â independent signaling pathways with relevance to inflammatory lung disease

He, Patrick, Gelissen, Ingrid C., Ammit, Alaina J.

Journal:

Respiratory Research

Year:

2020

File:

PDF, 823 KB

2020

5

Platelet activating factor (PAF) production by mouse embryos in vitro and its effect on embryonic metabolism

John P. Ryan, Neil R. Spinks, Christopher O'Neill, Alaina J. Ammit, Raymond G. Wales

Journal:

Journal of Cellular Biochemistry

Year:

1989

Language:

english

File:

PDF, 549 KB

english, 1989

6

Dual ERK and phosphatidylinositol 3-kinase pathways control airway smooth muscle proliferation: Differences in asthma

Janette K. Burgess, Jin Hee Lee, Qi Ge, Emma E. Ramsay, Maree H. Poniris, Johannes Parmentier, Michael Roth, Peter R.A. Johnson, Nicholas H. Hunt, Judith L. Black, Alaina J. Ammit

Journal:

Journal of Cellular Physiology

Year:

2008

Language:

english

File:

PDF, 235 KB

english, 2008

7

Preparation and evaluation of controlled release microparticles for respiratory protein therapy

Rania O. Salama, Daniela Traini, Hak-Kim Chan, Adrian Sung, Alaina J. Ammit, Paul M. Young

Journal:

Journal of Pharmaceutical Sciences

Year:

2009

Language:

english

File:

PDF, 242 KB

english, 2009

8

Pulmonary Spray Dried Powders of Tobramycin Containing Sodium Stearate to Improve Aerosolization Efficiency

Chiara Parlati, Paolo Colombo, Francesca Buttini, Paul M. Young, Handoko Adi, Alaina J. Ammit, Daniela Traini

Journal:

Pharmaceutical Research

Year:

2009

Language:

english

File:

PDF, 322 KB

english, 2009

9

G-Protein-coupled receptor agonists differentially regulate basal or tumor necrosis factor-α-stimulated activation of interleukin-6 and RANTES in human airway smooth muscle cells

Chien-Da Huang, Alaina J. Ammit, Omar Tliba, Han-Pin Kuo, Raymond B. Penn, Reynold A. Panettieri, Yassine Amrani

Journal:

Journal of Biomedical Science

Year:

2005

Language:

english

File:

PDF, 322 KB

english, 2005

10

Effect of St John's wort and ginseng on the pharmacokinetics and pharmacodynamics of warfarin in healthy subjects

Xuemin Jiang, Kenneth M. Williams, Winston S. Liauw, Alaina J. Ammit, Basil D. Roufogalis, Colin C. Duke, Richard O. Day, Andrew J. McLachlan

Journal:

British Journal of Clinical Pharmacology

Year:

2004

Language:

english

File:

PDF, 128 KB

english, 2004

11

Effect of ginkgo and ginger on the pharmacokinetics and pharmacodynamics of warfarin in healthy subjects

Xuemin Jiang, Kenneth M. Williams, Winston S. Liauw, Alaina J. Ammit, Basil D. Roufogalis, Colin C. Duke, Richard O. Day, Andrew J. McLachlan

Journal:

British Journal of Clinical Pharmacology

Year:

2005

Language:

english

File:

PDF, 189 KB

english, 2005

12

MEDIATORS ON HUMAN AIRWAY SMOOTH MUSCLE : Proceedings of the Australian Physiological and Pharmacological Society 1996 Symposium: Development of Bronchial Responsiveness

Carol Armour, Peter Johnson, Sinthia Anticevich, Alaina Ammit, Karen McKay, Margaret Hughes, Judith Black

Journal:

Clinical and Experimental Pharmacology and Physiology

Year:

1997

Language:

english

File:

PDF, 436 KB

english, 1997

13

Platelet-activating factor (PAF) receptor antagonists inhibit arachidonic acid induced platelet aggregation in rabbit whole blood

Alaina Jean Ammit, Chris O'Neill

Journal:

Year:

1991

Language:

english

File:

PDF, 422 KB

english, 1991

14

Proteasomal inhibition upregulates the endogenous MAPK deactivator MKP-1 in human airway smooth muscle: Mechanism of action and effect on cytokine secretion

John P. Moutzouris, Wenchi Che, Emma E. Ramsay, Melanie Manetsch, Hatem Alkhouri, Anna M. Bjorkman, Friederike Schuster, Qi Ge, Alaina J. Ammit

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

2010

Language:

english

File:

PDF, 850 KB

english, 2010

15

Estradiol stabilizes the 105-kDa phospho-form of the adhesion docking protein NEDD9 and suppresses NEDD9-dependent cell spreading in breast cancer cells

Lauren N. Bradshaw, J. Zhong, P. Bradbury, Maha Mahmassani, Jessica L. Smith, Alaina J. Ammit, Geraldine M. O'Neill

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

2011

Language:

english

File:

PDF, 750 KB

english, 2011

16

MKP-1: A negative feedback effector that represses MAPK-mediated pro-inflammatory signaling pathways and cytokine secretion in human airway smooth muscle cells

Melanie Manetsch, Wenchi Che, Petra Seidel, Yang Chen, Alaina J. Ammit

Journal:

Cellular Signalling

Year:

2012

Language:

english

File:

PDF, 680 KB

english, 2012

17

Novel p38 MAPK inhibitor ML3403 has potent anti-inflammatory activity in airway smooth muscle

Lenka Munoz, Emma E. Ramsay, Melanie Manetsch, Qi Ge, Christian Peifer, Stefan Laufer, Alaina J. Ammit

Journal:

European Journal of Pharmacology

Year:

2010

Language:

english

File:

PDF, 679 KB

english, 2010

18

Targeting p38 MAPK pathway for the treatment of Alzheimer's disease

Lenka Munoz, Alaina J. Ammit

Journal:

Neuropharmacology

Year:

2010

Language:

english

File:

PDF, 301 KB

english, 2010

19

The role of mRNA stability in airway remodelling

Alaina J. Ammit

Journal:

Pulmonary Pharmacology & Therapeutics

Year:

2005

Language:

english

File:

PDF, 185 KB

english, 2005

20

The effect of asthma therapeutics on signalling and transcriptional regulation of airway smooth muscle function

Alaina J. Ammit, Janette K. Burgess, Stuart J. Hirst, J. Margaret Hughes, Manminder Kaur, Justine Y. Lau, Suzanne Zuyderduyn

Journal:

Pulmonary Pharmacology & Therapeutics

Year:

2009

Language:

english

File:

PDF, 196 KB

english, 2009

21

Airways smooth muscle: The next generation

Alaina Ammit, Andrew J. Halayko, Stuart J. Hirst, Tom Murphy, Alastair Stewart

Journal:

Pulmonary Pharmacology & Therapeutics

Year:

2009

Language:

english

File:

PDF, 70 KB

english, 2009

22

Effective anti-platelet and COX-1 enzyme inhibitors from pungent constituents of ginger

Effie Nurtjahja-Tjendraputra, Alaina J. Ammit, Basil D. Roufogalis, Van H. Tran, Colin C. Duke

Journal:

Thrombosis Research

Year:

2003

Language:

english

File:

PDF, 337 KB

english, 2003

23

Gingerols and Related Analogues Inhibit Arachidonic Acid-Induced Human Platelet Serotonin Release and Aggregation

Karen L.K Koo, Alaina J Ammit, Van H Tran, Colin C Duke, Basil D Roufogalis

Journal:

Thrombosis Research

Year:

2001

Language:

english

File:

PDF, 218 KB

english, 2001

24

Gypenosides derived from Gynostemma pentaphyllum suppress NO synthesis in murine macrophages by inhibiting iNOS enzymatic activity and attenuating NF-κB-mediated iNOS protein expression

Fugen Aktan, Sheridan Henness, Basil D Roufogalis, Alaina J Ammit

Journal:

Year:

2003

Language:

english

File:

PDF, 271 KB

english, 2003

25

Sphingosine 1-phosphate induces MKP-1 expression via p38 MAPK- and CREB-mediated pathways in airway smooth muscle cells

Wenchi Che, Melanie Manetsch, Timo Quante, Md. Mostafizur Rahman, Brijeshkumar S. Patel, Qi Ge, Alaina J. Ammit

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

2012

Language:

english

File:

PDF, 891 KB

english, 2012

26

IL-17A augments TNF-α–induced IL-6 expression in airway smooth muscle by enhancing mRNA stability

Henness, Sheridan, Johnson, Colleen K., Ge, Qi, Armour, Carol L., Hughes, J. Margaret, Ammit, Alaina J.

Journal:

Journal of Allergy and Clinical Immunology

Year:

2004

Language:

english

File:

PDF, 201 KB

english, 2004

27

The Nucleotide-Binding Domain and Leucine-Rich Repeat Protein–3 Inflammasome Is Not Activated in Airway Smooth Muscle Upon Toll-Like Receptor–2 Ligation

Hirota, Jeremy A., Im, Hanna, Rahman, Mostafizur M., Rumzhum, Nowshin N., Manetsch, Melanie, Pascoe, Chris D., Bunge, Kristin, Alkhouri, Hatem, Oliver, Brian G., Ammit, Alaina J.

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2013

Language:

english

File:

PDF, 731 KB

english, 2013

28

Regulation of pulmonary inflammation by mesenchymal cells

Alkhouri, Hatem, Poppinga, Wilfred Jelco, Tania, Navessa Padma, Ammit, Alaina, Schuliga, Michael

Journal:

Pulmonary Pharmacology & Therapeutics

Year:

2014

Language:

english

File:

PDF, 956 KB

english, 2014

29

Pro-inflammatory and immunomodulatory functions of airway smooth muscle: Emerging concepts

Xia, Yuxiu C., Redhu, Naresh Singh, Moir, Lyn M., Koziol-White, Cynthia, Ammit, Alaina J., Al-Alwan, Laila, Camoretti-Mercado, Blanca, Clifford, Rachel L.

Journal:

Pulmonary Pharmacology & Therapeutics

Year:

2013

Language:

english

File:

PDF, 604 KB

english, 2013

30

Multinuclear ruthenium( ii ) complexes as anticancer agents

Gorle, Anil K., Ammit, Alaina J., Wallace, Lynne, Keene, F. Richard, Collins, J. Grant

Journal:

New Journal of Chemistry

Year:

2014

Language:

english

File:

PDF, 1.44 MB

english, 2014

31

Analysis of montmorillonite clay as a vehicle in platinum anticancer drug delivery

Apps, Michael G., Ammit, Alaina J., Gu, Alice, Wheate, Nial J.

Journal:

Inorganica Chimica Acta

Year:

2014

Language:

english

File:

PDF, 483 KB

english, 2014

32

The CXCL10/CXCR3 Axis Mediates Human Lung Mast Cell Migration to Asthmatic Airway Smooth Muscle

Brightling, Christopher E., Ammit, Alaina J., Kaur, Davinder, Black, Judith L., Wardlaw, Andrew J., Hughes, J. Margaret, Bradding, Peter

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2005

Language:

english

File:

PDF, 428 KB

english, 2005

33

Role of dynamin in elongated cell migration in a 3D matrix

Lees, Justin G., Gorgani, Nick N., Ammit, Alaina J., McCluskey, Adam, Robinson, Phillip J., O'Neill, Geraldine M.

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

2015

Language:

english

File:

PDF, 1.89 MB

english, 2015

34

Repression of breast cancer cell growth by proteasome inhibitors in vitro : impact of mitogen-activated protein kinase phosphatase 1

Patel, Brijeshkumar S, Co, Wai Sie, Donat, Claudia, Wang, Mary, Che, Wenchi, Prabhala, Pavan, Schuster, Friederike, Schulz, Vera, Martin, Janet L, Ammit, Alaina J

Journal:

Cancer Biology & Therapy

Year:

2015

Language:

english

File:

PDF, 4.62 MB

english, 2015

35

Cyclin D1 in ASM Cells from Asthmatics Is Insensitive to Corticosteroid Inhibition

Allen, Jodi C., Seidel, Petra, Schlosser, Tobias, Ramsay, Emma E., Ge, Qi, Ammit, Alaina J.

Journal:

Journal of Allergy (Hindawi Publishing Corporation)

Year:

2012

Language:

english

File:

PDF, 945 KB

english, 2012

36

Temporal regulation of cytokine mRNA expression by tristetraprolin: dynamic control by p38 MAPK and MKP-1

Prabhala, Pavan, Bunge, Kristin, Rahman, Md. Mostafizur, Ge, Qi, Clark, Andrew R., Ammit, Alaina J.

Journal:

AJP Lung Cellular and Molecular Physiology

Year:

2015

Language:

english

File:

PDF, 1.90 MB

english, 2015

37

Sphingosine 1-phosphate Increases COX-2 Expression and PGE 2 Secretion: Effects on β 2 -adrenergic Receptor Desensitization

Rumzhum, Nowshin N, Rahman, Md. Mostafizur, Oliver, Brian G, Ammit, Alaina J

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2015

Language:

english

File:

PDF, 406 KB

english, 2015

38

Tumor Necrosis Factor- α –Induced Secretion of RANTES and Interleukin-6 from Human Airway Smooth Muscle Cells

Ammit, Alaina J., Lazaar, Aili L., Irani, Carla, O'Neill, Geraldine M., Gordon, Nancy D., Amrani, Yassine, Penn, Raymond B., Panettieri, Reynold A.

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2002

Language:

english

File:

PDF, 268 KB

english, 2002

39

Role of mitogen-activated protein kinase phosphatase-1 in corticosteroid insensitivity of chronic oxidant lung injury

Pinart, Mariona, Hussain, Farhana, Shirali, Sima, Li, Feng, Zhu, Jie, Clark, Andrew R., Ammit, Alaina J., Chung, Kian Fan

Journal:

European Journal of Pharmacology

Year:

2014

Language:

english

File:

PDF, 707 KB

english, 2014

40

Corticosteroids Inhibit S1P-Induced IL-6 Secretion From Human Airway Smooth Muscle via MKP-1-Mediated Repression of MSK1

Che, Wenchi, Parmentier, Johannes, Seidel, Petra, Manetsch, Melanie, Ramsay, Emma E, Alkhouri, Hatem, Ge, Qi, Armour, Carol L, Ammit, Alaina J

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2013

Language:

english

File:

PDF, 1.60 MB

english, 2013

41

Inhibitors of Phosphodiesterase 4, but Not Phosphodiesterase 3, Increase β 2 -Agonist–Induced Expression of Antiinflammatory Mitogen-Activated Protein Kinase Phosphatase 1 in Airway Smooth Muscle Cells

Patel, Brijeshkumar S., Prabhala, Pavan, Oliver, Brian G., Ammit, Alaina J.

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2015

Language:

english

File:

PDF, 788 KB

english, 2015

42

Activation of K-p21ras and N-p21ras, but Not H-p21ras, Is Necessary for Mitogen-Induced Human Airway Smooth-Muscle Proliferation

Ammit, Alaina J., Kane, Sibyl A., Panettieri, Reynold A.

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

1999

File:

PDF, 218 KB

1999

43

Gingerol Metabolite and a Synthetic Analogue Capsarol™ Inhibit Macrophage NF-κB-Mediated iNOS Gene Expression and Enzyme Activity

Aktan, Fugen, Henness, Sheridan, Tran, Van, Duke, Colin, Roufogalis, Basil, Ammit, Alaina

Journal:

Year:

2006

Language:

english

File:

PDF, 283 KB

english, 2006

44

Activation of K-p21ras and N-p21ras, but Not H-p21ras, Is Necessary for Mitogen-Induced Human Airway Smooth-Muscle Proliferation

Ammit, Alaina J., Kane, Sibyl A., Panettieri, Reynold A.

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

1999

Language:

english

File:

PDF, 218 KB

english, 1999

45

Tumor Necrosis Factor- α –Induced Secretion of RANTES and Interleukin-6 from Human Airway Smooth-Muscle Cells

Ammit, Alaina J., Hoffman, Rebecca K., Amrani, Yassine, Lazaar, Aili L., Hay, Douglas W. P., Torphy, Theodore J., Penn, Raymond B., Panettieri, Reynold A.

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2000

Language:

english

File:

PDF, 382 KB

english, 2000

46

Corticosteroids Reduce IL-6 in ASM Cells via Up-Regulation of MKP-1

Quante, Timo, Ng, Yee Ching, Ramsay, Emma E., Henness, Sheridan, Allen, Jodi C., Parmentier, Johannes, Ge, Qi, Ammit, Alaina J.

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2008

Language:

english

File:

PDF, 518 KB

english, 2008

47

Smooth-Muscle Myosin Light-Chain Kinase Content Is Increased in Human Sensitized Airways

AMMIT, ALAINA J., ARMOUR, CAROL L., BLACK, JUDITH L.

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2000

Language:

english

File:

PDF, 200 KB

english, 2000

48

Theophylline Represses IL-8 Secretion From ASM Cells Independently of PDE Inhibition: Novel Role as a PP2A Activator

Patel, Brijeshkumar S, Rahman, Md. Mostafizur, Rumzhum, Nowshin N, Oliver, Brian G, Verrills, Nicole M, Ammit, Alaina J

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2015

Language:

english

File:

PDF, 441 KB

english, 2015

49

Activating protein phosphatase 2A (PP2A) enhances tristetraprolin (TTP) anti-inflammatory function in A549 lung epithelial cells

Rahman, Md. Mostafizur, Rumzhum, Nowshin N., Hansbro, Philip M., Morris, Jonathan C., Clark, Andrew R., Verrills, Nicole M., Ammit, Alaina J.

Journal:

Cellular Signalling

Year:

2016

Language:

english

File:

PDF, 656 KB

english, 2016

50

[American Thoracic Society American Thoracic Society 2011 International Conference, May 13-18, 2011 • Denver Colorado - ()] B69. NOVEL INSIGHTS INTO AIRWAY INFLAMMATION AND REMODELING IN ASTHMA AND COPD - Corticosteroids Inhibit Sphingosine 1-Phosphate-Induced Il-6 Secretion From Airway Smooth Muscle Cells

Ammit, Alaina J., Che, Wenchi, Parmentier, Johannes, Seidel, Petra, Manetsch, Melanie, Quante, Timo, Ramsay, Emma E., Schulz, Vera, Schuster, Friederike, Henness, Sheridan, Allen, Jodi C., Ge, Qi, Arm

Year:

2011

Language:

english

File:

PDF, 20 KB

english, 2011

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